Activity record

PGDB_A039712

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

degradation = 20 %

TargetIKZF1
ConcentrationConcentration context: titrated doses of compound
Time24 h
Assay / Readoutflow_cytometry / % Degradation
Assay IDPGDB_AS000538
PatentCN121487946A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundCOMPARATIVE COMPOUND A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000538
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses of compound
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121487946A
Compound location

COMPARATIVE COMPOUND A

COMPARATIVE COMPOUND A enlarged structureCOMPARATIVE COMPOUND A location on patent page 69
Activity table
Page 77 · table single