Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Contact us

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A039733

Assay: % DegradationTarget: IKZF2QC: ambiguous

Activity overview

EC50 = 0.67 uM

TargetIKZF2

Cell line293GT

Time14 h

Assay / ReadoutEC50 / % Degradation

Assay IDPGDB_AS002503

PatentKR20210031923A

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C008954

CompoundMix of I-119 & I-121

Source record IDPGDB_C008954

InChIKeyDOOXHGVFAQUURQ-PYNWJHIZSA-N

Assay context

Assay IDPGDB_AS002503

Assay family% Degradation

Assay systemcell_based

ReadoutEC50

Treatment time14 h

Detection targetprotein_degradation

TargetIKZF2

E3Not specified

Cell line293GT

Source evidence

Patent IDKR20210031923A

Compound location

Mix of I-119 & I-121

Mix of I-119 & I-121 enlarged structure

Mix of I-119 & I-121 location on patent page 332

Activity table

Page 329 · table start

Page 330 · table middle

Page 331 · table middle

Page 332 · table middle

Page 333 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU