Activity record

PGDB_A040020

Assay: % DegradationTarget: SALL4QC: standardized
Activity overview

Dmax = 69.7 %

TargetSALL4
Cell lineHT-1080
ConcentrationConcentration context: HiBiT SALL4:_D max (%)
Time20 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001879
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009601
Compound IDPGDB_C009601
Compound泊马度胺
Source record IDPGDB_C000056
InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001879
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration context: HiBiT SALL4:_D max (%)
Treatment time20 h
Detection targetprotein_degradation
TargetSALL4
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

泊马度胺

泊马度胺 enlarged structure泊马度胺 location on patent page 122
Activity table
Page 121 · table single