Activity record

PGDB_A040114

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 3.2 nM

TargetGSPT1
Cell lineHNT-34
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000001
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005327
Compound IDPGDB_C005327
Compound4-133;4-133
Source record IDPGDB_C005327
InChIKeyCJOGJAGFAWIFTH-JKGBFCRXSA-N

Assay context

Assay IDPGDB_AS000001
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHNT-34

Source evidence

Patent IDWO2023078410A1
Compound location

4-133;4-133

4-133;4-133 enlarged structure4-133;4-133 location on patent page 19
Activity table
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