Activity record

PGDB_A040115

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

GI50 = 1.63 nM

TargetGSPT1
Cell lineToledo
Time48 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS002036
PatentWO2023237116A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002259
Compound IDPGDB_C002259
CompoundExample 70
Source record IDPGDB_C002259
InChIKeyILZJDMOZTPYGBG-ZRBYOGHPSA-N

Assay context

Assay IDPGDB_AS002036
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time48 h
Detection target% Cell viability
TargetGSPT1
E3Not specified
Cell lineToledo

Source evidence

Patent IDWO2023237116A1
Compound location

Example 70

Example 70 enlarged structureExample 70 location on patent page 241
Activity table
Page 384 · table single