Activity record

PGDB_A040286

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

Dmax = 92 %

TargetIKZF2
Time13 d
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS000562
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundComparative Compound A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000562
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

Comparative Compound A

Comparative Compound A enlarged structureComparative Compound A location on patent page 86
Activity table
Page 92 · table single