Activity record

PGDB_A040421

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 5.9 nM

TargetGSPT1
Cell lineNCI-H1581
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000790
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001868
Compound IDPGDB_C001868
CompoundWX016
Source record IDPGDB_C001868
InChIKeyUSEQRCHYCVHABT-GOSISDBHSA-N

Assay context

Assay IDPGDB_AS000790
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H1581

Source evidence

Patent IDWO2023001028A1
Compound location

WX016

WX016 enlarged structureWX016 location on patent page 39
Activity table
Page 47 · table single