Activity record

PGDB_A040527

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

Dmax = 1.2 %

TargetGSPT1
Cell lineHEK293
Concentration10 uM
Time6 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS000429
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007975
Compound IDPGDB_C007975
Compound70;70
Source record IDPGDB_C007975
InChIKeyDINZUNGBAAZGNJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000429
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Concentration10 uM
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineHEK293

Source evidence

Patent IDWO2025043225
Compound location

70;70

70;70 enlarged structure70;70 location on patent page 24
Activity table
Page 527 · table start
Page 528 · table end