Activity record

PGDB_A040550

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 1-1.5 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS002101
PatentWO2024245444A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C014239
Compound IDPGDB_C014239
CompoundGT-06132
Source record IDPGDB_C014239
InChIKeyFRYVOXFJZUZNEK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002101
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2024245444A1
Compound location

GT-06132

GT-06132 enlarged structureGT-06132 location on patent page 107
Activity table
Page 260 · table single