Activity record

PGDB_A041130

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

DC50 = 2.9 nM

TargetIKZF2
Time20 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS001421
PatentCN121646585A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007381
Compound IDPGDB_C007381
CompoundCOMPARATIVE COMPOUND A
Source record IDPGDB_C007381
InChIKeyOHSPSWUQMQUVMW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001421
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time20 h
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121646585A
Compound location

COMPARATIVE COMPOUND A

COMPARATIVE COMPOUND A enlarged structureCOMPARATIVE COMPOUND A location on patent page 71
Activity table
Page 75 · table single