Activity record

PGDB_A041141

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

EC50 = 0.025 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutEC50 / binding
Assay IDPGDB_AS001482
PatentUS20230265071A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000417
Compound IDPGDB_C000417
Compound69
Source record IDPGDB_C000417
InChIKeyADTJOHKRUYWZNE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001482
Assay familybinding
Assay systembiochemical
ReadoutEC50
TargetCRBN
E3CRBN

Source evidence

Patent IDUS20230265071A1
Compound location

69

69 enlarged structure69 location on patent page 44
Activity table
Page 166 · table start
Page 167 · table middle
Page 168 · table middle
Page 169 · table end