Activity record

PGDB_A041319

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 30-40 %

TargetIKZF3
Cell lineMM.1S
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS002484
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024416
Compound IDPGDB_C024416
CompoundGT-10414
Source record IDPGDB_C024416
InChIKeyXINHVJZNKZNOPU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002484
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineMM.1S
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10414

GT-10414 enlarged structureGT-10414 location on patent page 33
Activity table
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