Activity record

PGDB_A041437

Assay: % DegradationTarget: IKZF4QC: ambiguous
Activity overview

DC50 > 1000 nM

TargetIKZF4
Time13 d
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS002480
PatentCN121368591A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007373
Compound IDPGDB_C007373
CompoundCOMPARATIVE COMPOUND B
Source record IDPGDB_C007373
InChIKeyVACYFJWFXFNBTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002480
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF4
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121368591A
Compound location

COMPARATIVE COMPOUND B

COMPARATIVE COMPOUND B enlarged structureCOMPARATIVE COMPOUND B location on patent page 74
Activity table
Page 81 · table single