Activity record

PGDB_A041589

Assay: viabilityTarget: BRAFQC: standardized
Activity overview

IC50 > 1000 nM

TargetBRAF
Cell lineA375
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002189
PatentCN121181579A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024605
Compound IDPGDB_C024605
Compound实施例62;实施例62
Source record IDPGDB_C024605
InChIKeyFFEBAJCQPNVNNV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002189
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection targetcell_proliferation
TargetBRAF
E3Not specified
Cell lineA375
OrganismHomo sapiens

Source evidence

Patent IDCN121181579A
Compound location

实施例62;实施例62

实施例62;实施例62 enlarged structure实施例62;实施例62 location on patent page 29
Activity table
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