Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C024605
12 activity records1 related patents
2D structure
CCn1c2c(-c3cc(C#CC(C)(C)C(=O)N(C)C)cnc3C(C)OC)c3cc(ccc31)-c1csc(n1)CC(NC(=O)C1C(C)C1C)C(=O)N1NC(C(=O)OCC(C)(C)C2)C2CC1C2Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 6.303 | nM | - | — | KRAS | - | - | CN121181579A | PGDB_A016259 | PGDB_C024605 | PGDB_AS000377 | View |
| IC50 | - | = | 1.764 | nM | - | — | KRAS | - | AsPC-1 | CN121181579A | PGDB_A017494 | PGDB_C024605 | PGDB_AS001203 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AsPC-1 | CN121181579A | PGDB_A020459 | PGDB_C024605 | PGDB_AS001095 | View |
| IC50 | - | = | 0.7981 | nM | - | — | KRAS | - | AGS | CN121181579A | PGDB_A023337 | PGDB_C024605 | PGDB_AS000782 | View |
| IC50 | - | = | 0.2682 | nM | - | — | KRAS | - | SW620 | CN121181579A | PGDB_A024499 | PGDB_C024605 | PGDB_AS001545 | View |
| IC50 | - | = | 39.37 | nM | - | — | KRAS | - | - | CN121181579A | PGDB_A027753 | PGDB_C024605 | PGDB_AS000617 | View |
| IC50 | - | > | 1000 | nM | - | — | BRAF | - | A375 | CN121181579A | PGDB_A041589 | PGDB_C024605 | PGDB_AS002189 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | HPAC | CN121181579A | PGDB_A044684 | PGDB_C024605 | PGDB_AS000097 | View |
| IC50 | - | = | 0.4508 | nM | - | — | KRAS | - | NCI-H358 | CN121181579A | PGDB_A061320 | PGDB_C024605 | PGDB_AS002403 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | NCI-H358 | CN121181579A | PGDB_A065911 | PGDB_C024605 | PGDB_AS000504 | View |
| IC50 | - | <= | 10 | nM | - | — | - | - | MIA PaCa-2 | CN121181579A | PGDB_A067944 | PGDB_C024605 | PGDB_AS001225 | View |
| IC50 | - | <= | 10 | nM | - | — | KRAS | - | AGS | CN121181579A | PGDB_A070498 | PGDB_C024605 | PGDB_AS000586 | View |