Activity record

PGDB_A041813

Assay: biochemicalQC: ambiguous
Activity overview

selectivity_index = 0.494 fold

Time60 min
ControlCDK7 / CDK12
Assay / ReadoutFold change / biochemical
Assay IDPGDB_AS002236
PatentCN114929708B
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006566
Compound IDPGDB_C006566
CompoundREF-002
Source record IDPGDB_C006566
InChIKeyVTMQFTUFJZPBDS-AEFFLSMTSA-N

Assay context

Assay IDPGDB_AS002236
Assay familybiochemical
Assay systembiochemical
ReadoutFold change
Treatment time60 min
TargetCDK12 | CDK7
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN114929708B
Compound location

REF-002

REF-002 enlarged structureREF-002 location on patent page 195
Activity table
Page 195 · table start
Page 196 · table middle
Page 197 · table end