Activity record

PGDB_A041904

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 2.24 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000788
PatentWO2023151635A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001191
Compound IDPGDB_C001191
CompoundGT-03227
Source record IDPGDB_C001191
InChIKeyIRCMUBVGAXOBGL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000788
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2023151635A1
Compound location

GT-03227

GT-03227 enlarged structureGT-03227 location on patent page 284
Activity table
Page 358 · table single