Activity record

PGDB_A041941

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 40-53 %

TargetCRBN
E3 ligaseCRBN
Concentration2 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS001462
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000749
Compound IDPGDB_C000749
CompoundGT-09842
Source record IDPGDB_C000749
InChIKeyFLSMXUNGQPDLQU-NQCNTLBGSA-N

Assay context

Assay IDPGDB_AS001462
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration2 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09842

GT-09842 enlarged structureGT-09842 location on patent page 39
Activity table
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