Activity record

PGDB_A042128

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

Dmax = 17 %

TargetIKZF1
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001079
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007373
Compound IDPGDB_C007373
CompoundComparative Compound B
Source record IDPGDB_C007373
InChIKeyVACYFJWFXFNBTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001079
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 101
Activity table
Page 111 · table single