Activity record

PGDB_A042227

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 3.429 nM

TargetKRAS
Time1.5 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000377
PatentCN121181579A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024617
Compound IDPGDB_C024617
Compound实施例74
Source record IDPGDB_C024617
InChIKeyAOBNEHSSSIAOMU-AAHLPCHMSA-N

Assay context

Assay IDPGDB_AS000377
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1.5 h
TargetKRAS
E3Not specified

Source evidence

Patent IDCN121181579A
Compound location

实施例74

实施例74 enlarged structure实施例74 location on patent page 30
Activity table
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