Activity record

PGDB_A042612

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

GI50 = 78 nM

TargetGSPT1
Cell lineNCI-H1155
Time72 h
Assay / ReadoutGI50 / viability
Assay IDPGDB_AS000187
PatentWO2024222614A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003209
Compound IDPGDB_C003209
Compound35;化合物 35
Source record IDPGDB_C003209
InChIKeyHRLVEYLJTJHYBK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000187
Assay familyviability
Assay systemcell_based
ReadoutGI50
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDWO2024222614A1
Compound location

35;化合物 35

35;化合物 35 enlarged structure35;化合物 35 location on patent page 16
Activity table
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