Activity record

PGDB_A042690

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 20-30 %

TargetCRBN
E3 ligaseCRBN
Concentration0.5 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS002000
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000804
Compound IDPGDB_C000804
CompoundGT-09350
Source record IDPGDB_C000804
InChIKeyMLJWTEFSPFNVRK-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002000
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration0.5 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09350

GT-09350 enlarged structureGT-09350 location on patent page 26
Activity table
Page 147 · table start
Page 148 · table end