Activity record

PGDB_A043215

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 1-10 uM

TargetCRBN
E3 ligaseCRBN
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001252
PatentWO2022066835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019578
Compound IDPGDB_C019578
Compound76;76
Source record IDPGDB_C001371
InChIKeyIKDVSFZRINDHDU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001252
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022066835A1
Compound location

76;76

76;76 enlarged structure76;76 location on patent page 188
Activity table
Page 165 · table single