Activity record

PGDB_A043447

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 0.067 uM

TargetGSPT1
Cell line293A
Time6 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001164
PatentCN121591645A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001074
Compound IDPGDB_C001074
Compound5A;5A
Source record IDPGDB_C001074
InChIKeyNESFVBJSTVKDNX-UUVAVEHKSA-N

Assay context

Assay IDPGDB_AS001164
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time6 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell line293A

Source evidence

Patent IDCN121591645A
Compound location

5A;5A

5A;5A enlarged structure5A;5A location on patent page 3
Activity table
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