Activity record

PGDB_A044092

Assay: viabilityTarget: PDE3AQC: standardized
Activity overview

IC50 = 5.3 nM

TargetPDE3A
Cell lineSK-MEL-3
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000487
PatentCN118420559B
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006826
Compound IDPGDB_C006826
Compound2;2;实施例2
Source record IDPGDB_C006826
InChIKeyYRYSNJRREQGBOS-QBQQXWOESA-N

Assay context

Assay IDPGDB_AS000487
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
Detection targetcell_proliferation
TargetPDE3A
E3Not specified
Cell lineSK-MEL-3

Source evidence

Patent IDCN118420559B
Compound location

2;2;实施例2

2;2;实施例2 enlarged structure2;2;实施例2 location on patent page 26
Activity table
Page 26 · table single