Assay

PGDB_AS000487

System: cell_basedCell line: SK-MEL-3
Assay context summary

Assay context

12 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
E3Not specified
Cell lineSK-MEL-3
Detection targetcell_proliferation
Activity compounds and values

Activity records

12 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C006834
IC50-=3.4nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A007241PGDB_C006834PGDB_AS000487View
2D structure for PGDB_C006831
IC50-=0.6nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A017130PGDB_C006831PGDB_AS000487View
2D structure for PGDB_C006824
IC50-=2.4nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A021552PGDB_C006824PGDB_AS000487View
2D structure for PGDB_C006829
IC50-=1.1nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A024746PGDB_C006829PGDB_AS000487View
2D structure for PGDB_C006833
IC50-=5nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A026553PGDB_C006833PGDB_AS000487View
2D structure for PGDB_C006828
IC50-=0.5nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A035314PGDB_C006828PGDB_AS000487View
2D structure for PGDB_C006826
IC50-=5.3nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A044092PGDB_C006826PGDB_AS000487View
2D structure for PGDB_C006832
IC50-=2.3nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A048362PGDB_C006832PGDB_AS000487View
2D structure for PGDB_C006825
IC50-=6.5nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A057697PGDB_C006825PGDB_AS000487View
2D structure for PGDB_C006830
IC50-=2nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A064554PGDB_C006830PGDB_AS000487View
2D structure for PGDB_C006827
IC50-=0.3nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A071563PGDB_C006827PGDB_AS000487View
2D structure for PGDB_C006823
IC50-=2.9nM-—PDE3A-SK-MEL-3CN118420559BPGDB_A074951PGDB_C006823PGDB_AS000487View
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