PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN118420559B

AssigneeShanghai Chaoyang Pharmaceutical

TitleDeuterated oxadiazinone compounds and uses thereof

Family ID92325982

Family members2

Filing year2024

Publication date2025-02-14

JurisdictionCN

Compounds12

Activity records18

Assays3

Activity compounds and values

Activity records

18 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	205.7	nM	-	—	PDE3A	-	-	PGDB_A007209	PGDB_C006823	PGDB_AS002332	View
IC50	-	=	3.4	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A007241	PGDB_C006834	PGDB_AS000487	View
IC50	-	=	0.6	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A017130	PGDB_C006831	PGDB_AS000487	View
IC50	-	=	2.4	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A021552	PGDB_C006824	PGDB_AS000487	View
IC50	-	=	1.1	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A024746	PGDB_C006829	PGDB_AS000487	View
IC50	-	=	5	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A026553	PGDB_C006833	PGDB_AS000487	View
IC50	-	=	741	nM	-	—	PDE3A	-	-	PGDB_A028956	PGDB_C006828	PGDB_AS002332	View
IC50	-	=	0.5	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A035314	PGDB_C006828	PGDB_AS000487	View
IC50	-	=	236.8	nM	-	—	PDE3A	-	-	PGDB_A035634	PGDB_C006824	PGDB_AS002332	View
IC50	-	=	5.3	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A044092	PGDB_C006826	PGDB_AS000487	View
IC50	-	=	2.3	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A048362	PGDB_C006832	PGDB_AS000487	View
IC50	-	=	5.4	nM	-	—	PDE3A	-	A2058	PGDB_A053698	PGDB_C006827	PGDB_AS002220	View
IC50	-	=	13.2	nM	-	—	PDE3A	-	A2058	PGDB_A056383	PGDB_C006823	PGDB_AS002220	View
IC50	-	=	6.5	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A057697	PGDB_C006825	PGDB_AS000487	View
IC50	-	=	2	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A064554	PGDB_C006830	PGDB_AS000487	View
IC50	-	=	901.8	nM	-	—	PDE3A	-	-	PGDB_A067488	PGDB_C006827	PGDB_AS002332	View
IC50	-	=	0.3	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A071563	PGDB_C006827	PGDB_AS000487	View
IC50	-	=	2.9	nM	-	—	PDE3A	-	SK-MEL-3	PGDB_A074951	PGDB_C006823	PGDB_AS000487	View

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