Activity record

PGDB_A044221

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 1-10 nM

TargetKRAS
Time1 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS001818
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011606
Compound IDPGDB_C011606
CompoundExample 19
Source record IDPGDB_C011606
InChIKeyGIWORAYCLGMUDM-BYCNTYIMSA-N

Assay context

Assay IDPGDB_AS001818
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1 h
TargetRAF1
E3Not specified

Source evidence

Patent IDWO2025214350A1
Compound location

Example 19

Example 19 enlarged structureExample 19 location on patent page 58
Activity table
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