Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A044329

Assay: % DegradationTarget: SALL4QC: standardized

Activity overview

Dmax = 59.4 %

TargetSALL4

Cell lineHT-1080

ConcentrationConcentration context: HiBiT SALL4: D max (%)

Time20 h

Assay / Readoutluminescence / Dmax

Assay IDPGDB_AS001601

PatentEP4393915A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C007553

Compound化合物 9-B

Source record IDPGDB_C007553

InChIKeyHULAZOQCQMEDII-HKBQPEDESA-N

Assay context

Assay IDPGDB_AS001601

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

Technologyluminescence

ConcentrationConcentration context: HiBiT SALL4: D max (%)

Treatment time20 h

Detection targetprotein_degradation

TargetSALL4 | GSPT1

E3Not specified

Cell lineHT-1080

OrganismHomo sapiens

Source evidence

Patent IDEP4393915A1

Compound location

化合物 9-B

化合物 9-B enlarged structure

化合物 9-B location on patent page 109

Activity table

Page 121 · table single

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU