Activity record

PGDB_A044367

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 = 0.28 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS001908
PatentWO2025043225
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007956
Compound IDPGDB_C007956
Compound25;25;25
Source record IDPGDB_C007956
InChIKeyJBXJEWXBDNESRU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001908
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

25;25;25

25;25;25 enlarged structure25;25;25 location on patent page 21
Activity table
Page 525 · table start
Page 526 · table end