Assay

PGDB_AS001908

System: biochemicalTarget: CRBN
Assay context summary

Assay context

30 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Activity compounds and values

Activity records

30 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C007941
IC50-=0.084uM-—CRBNCRBN-WO2025043225PGDB_A007254PGDB_C007941PGDB_AS001908View
2D structure for PGDB_C007945
IC50-=0.15uM-—CRBNCRBN-WO2025043225PGDB_A017287PGDB_C007945PGDB_AS001908View
2D structure for PGDB_C007953
IC50-=1.2uM-—CRBNCRBN-WO2025043225PGDB_A017920PGDB_C007953PGDB_AS001908View
2D structure for PGDB_C007966
IC50-=0.068uM-—CRBNCRBN-WO2025043225PGDB_A026591PGDB_C007966PGDB_AS001908View
2D structure for PGDB_C007969
IC50-=0.022uM-—CRBNCRBN-WO2025043225PGDB_A026954PGDB_C007969PGDB_AS001908View
2D structure for PGDB_C007934
IC50-=1.1uM-—CRBNCRBN-WO2025043225PGDB_A027251PGDB_C007934PGDB_AS001908View
2D structure for PGDB_C007959
IC50-=0.058uM-—CRBNCRBN-WO2025043225PGDB_A028701PGDB_C007959PGDB_AS001908View
2D structure for PGDB_C007961
IC50-=0.14uM-—CRBNCRBN-WO2025043225PGDB_A028752PGDB_C007961PGDB_AS001908View
2D structure for PGDB_C007940
IC50-=0.44uM-—CRBNCRBN-WO2025043225PGDB_A029984PGDB_C007940PGDB_AS001908View
2D structure for PGDB_C007952
IC50-=0.076uM-—CRBNCRBN-WO2025043225PGDB_A030827PGDB_C007952PGDB_AS001908View
2D structure for PGDB_C007942
IC50-=0.094uM-—CRBNCRBN-WO2025043225PGDB_A031267PGDB_C007942PGDB_AS001908View
2D structure for PGDB_C007932
IC50-=0.19uM-—CRBNCRBN-WO2025043225PGDB_A037987PGDB_C007932PGDB_AS001908View
2D structure for PGDB_C007939
IC50-=0.22uM-—CRBNCRBN-WO2025043225PGDB_A041245PGDB_C007939PGDB_AS001908View
2D structure for PGDB_C007968
IC50-=0.063uM-—CRBNCRBN-WO2025043225PGDB_A042485PGDB_C007968PGDB_AS001908View
2D structure for PGDB_C007933
IC50-=0.041uM-—CRBNCRBN-WO2025043225PGDB_A042490PGDB_C007933PGDB_AS001908View
2D structure for PGDB_C007956
IC50-=0.28uM-—CRBNCRBN-WO2025043225PGDB_A044367PGDB_C007956PGDB_AS001908View
2D structure for PGDB_C007946
IC50-=0.77uM-—CRBNCRBN-WO2025043225PGDB_A052175PGDB_C007946PGDB_AS001908View
2D structure for PGDB_C007947
IC50-=0.18uM-—CRBNCRBN-WO2025043225PGDB_A053855PGDB_C007947PGDB_AS001908View
2D structure for PGDB_C007950
IC50-=0.15uM-—CRBNCRBN-WO2025043225PGDB_A055497PGDB_C007950PGDB_AS001908View
2D structure for PGDB_C007960
IC50-=0.055uM-—CRBNCRBN-WO2025043225PGDB_A056137PGDB_C007960PGDB_AS001908View
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