Activity record

PGDB_A044474

Assay: viabilityTarget: GSPT1QC: manual_curated
Activity overview

IC50 = 10-100 nM

TargetGSPT1
Cell lineKG-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002114
PatentWO2024222918A1
QC statusmanual_curated
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003253
Compound IDPGDB_C003253
Compound化合物A-35
Source record IDPGDB_C003253
InChIKeySIUIFCAGGADHCH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002114
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineKG-1

Source evidence

Patent IDWO2024222918A1
Compound location

化合物A-35

化合物A-35 enlarged structure化合物A-35 location on patent page 42
Activity table
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