Activity record

PGDB_A044612

Assay: % DegradationQC: ambiguous
Activity overview

DC50 = 22 nM

Cell lineMM.1S
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001567
PatentWO2022219412A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001770
Compound IDPGDB_C001770
Compound45
Source record IDPGDB_C001770
InChIKeyFHSWTCHLPBCKFQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001567
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TargetIKZF1 | IKZF3
E3Not specified
Cell lineMM.1S

Source evidence

Patent IDWO2022219412A1
Compound location

45

45 enlarged structure45 location on patent page 112
Activity table
Page 171 · table single