Activity record

PGDB_A044721

Assay: viabilityTarget: CCNKQC: ambiguous
Activity overview

GI50 < 1000 nM

TargetCCNK
Cell lineK562
Time144 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS000413
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C012010
Compound IDPGDB_C012010
Compound145;145
Source record IDPGDB_C012010
InChIKeyNKCUSTMEOSVVLY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000413
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time144 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
Cell lineK562
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

145;145

145;145 enlarged structure145;145 location on patent page 78
Activity table
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