Activity record

PGDB_A044816

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

DC50 = 0.292 uM

TargetIKZF2
Cell lineHEK293T
Time24 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS002469
PatentUS20230265071A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000384
Compound IDPGDB_C000384
Compound14
Source record IDPGDB_C000384
InChIKeyDQYZQRGRHXEYPT-DSNGMDLFSA-N

Assay context

Assay IDPGDB_AS002469
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time24 h
TargetIKZF2
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDUS20230265071A1
Compound location

14

14 enlarged structure14 location on patent page 32
Activity table
Page 166 · table single