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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A044876

Assay: % DegradationTarget: IKZF2QC: ambiguous

Activity overview

degradation = 0.83 %

TargetIKZF2

Cell line293GT

Concentration10 uM

Time24 h

Assay / Readoutluminescence / % Degradation

Assay IDPGDB_AS000887

PatentKR20210031680A

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C008810

CompoundI-139

Source record IDPGDB_C008810

InChIKeyIVYCUMBWYRMWMB-SUICTNHXSA-N

Assay context

Assay IDPGDB_AS000887

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

Technologyluminescence

Concentration10 uM

Treatment time24 h

Detection targetprotein_degradation

TargetIKZF2

E3Not specified

Cell line293GT

Source evidence

Patent IDKR20210031680A

Compound location

I-139

I-139 enlarged structure

I-139 location on patent page 487

Activity table

Page 558 · table start

Page 559 · table middle

Page 560 · table middle

Page 561 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU