PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

186 activity records

Assay family% Degradation

Systemcell_based

Readout% Degradation

TargetIKZF2

E3Not specified

Cell line293GT

Technologyluminescence

Detection targetprotein_degradation

Activity compounds and values

Activity records

186 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
% Degradation	-	=	67	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A007118	PGDB_C008906	PGDB_AS000887	View
% Degradation	-	=	0.77	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A007441	PGDB_C008811	PGDB_AS000887	View
% Degradation	-	=	0	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A007554	PGDB_C008787	PGDB_AS000887	View
% Degradation	-	=	0.75	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A007654	PGDB_C008829	PGDB_AS000887	View
% Degradation	-	=	85	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A008650	PGDB_C008924	PGDB_AS000887	View
% Degradation	-	=	70	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A009615	PGDB_C008911	PGDB_AS000887	View
% Degradation	-	=	80	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A009851	PGDB_C008776	PGDB_AS000887	View
% Degradation	-	=	35	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A010043	PGDB_C008879	PGDB_AS000887	View
% Degradation	-	=	0.7	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A010810	PGDB_C008826	PGDB_AS000887	View
% Degradation	-	=	56	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A011289	PGDB_C008916	PGDB_AS000887	View
% Degradation	-	=	82	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A011347	PGDB_C008910	PGDB_AS000887	View
% Degradation	-	=	2	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A011454	PGDB_C008837	PGDB_AS000887	View
% Degradation	-	=	0.77	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A011508	PGDB_C008819	PGDB_AS000887	View
% Degradation	-	=	0.83	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A012025	PGDB_C008824	PGDB_AS000887	View
% Degradation	-	=	93	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A012834	PGDB_C008902	PGDB_AS000887	View
% Degradation	-	=	80	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A013530	PGDB_C008914	PGDB_AS000887	View
% Degradation	-	=	88	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A014921	PGDB_C008923	PGDB_AS000887	View
% Degradation	-	=	75	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A014991	PGDB_C008836	PGDB_AS000887	View
% Degradation	-	=	75	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A015085	PGDB_C008919	PGDB_AS000887	View
% Degradation	-	=	88	%	10 uM	24 h	IKZF2	-	293GT	KR20210031680A	PGDB_A015351	PGDB_C008868	PGDB_AS000887	View

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