Activity record

PGDB_A045044

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 5.6 nM

TargetGSPT1
Cell lineDMS114
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000425
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001867
Compound IDPGDB_C001867
CompoundWX015
Source record IDPGDB_C001867
InChIKeyUSEQRCHYCVHABT-SFHVURJKSA-N

Assay context

Assay IDPGDB_AS000425
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineDMS114

Source evidence

Patent IDWO2023001028A1
Compound location

WX015

WX015 enlarged structureWX015 location on patent page 39
Activity table
Page 47 · table single