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Compound
PGDB_C001867
8 activity records1 related patents
2D structure
COCCOc1cc(NC(=O)NCc2ccc3c([C@@H]4CCC(=O)NC4=O)coc3c2)cc(Cl)c1CCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 67.66 | % | - | 3 d | GSPT1 | - | NCI-H69 | WO2023001028A1 | PGDB_A008026 | PGDB_C001867 | PGDB_AS002018 | View |
| IC50 | - | = | 5 | nM | - | — | GSPT1 | - | NCI-H1581 | WO2023001028A1 | PGDB_A010116 | PGDB_C001867 | PGDB_AS000790 | View |
| IC50 | - | = | 6.9 | nM | - | — | GSPT1 | - | NCI-H69 | WO2023001028A1 | PGDB_A016946 | PGDB_C001867 | PGDB_AS001964 | View |
| % Inhibition | - | = | 99.44 | % | - | 3 d | GSPT1 | - | NCI-H526 | WO2023001028A1 | PGDB_A019296 | PGDB_C001867 | PGDB_AS000350 | View |
| IC50 | - | = | 5.6 | nM | - | — | GSPT1 | - | DMS114 | WO2023001028A1 | PGDB_A045044 | PGDB_C001867 | PGDB_AS000425 | View |
| IC50 | - | = | 0.5 | nM | - | — | GSPT1 | - | NCI-H526 | WO2023001028A1 | PGDB_A049248 | PGDB_C001867 | PGDB_AS001706 | View |
| % Inhibition | - | = | 91.87 | % | - | 3 d | GSPT1 | - | NCI-H1581 | WO2023001028A1 | PGDB_A049718 | PGDB_C001867 | PGDB_AS000288 | View |
| % Inhibition | - | = | 90.22 | % | - | 3 d | GSPT1 | - | DMS114 | WO2023001028A1 | PGDB_A064875 | PGDB_C001867 | PGDB_AS001771 | View |