Activity record

PGDB_A045303

Assay: % DegradationTarget: BRD4QC: standardized
Activity overview

DC50 < 10 nM

TargetBRD4
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS000558
PatentEP4605088A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007731
Compound IDPGDB_C007731
Compound217;217
Source record IDPGDB_C007731
InChIKeyMGVBYJKVGYUDBM-RVJZANQKSA-N

Assay context

Assay IDPGDB_AS000558
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
TargetBRD4
E3Not specified

Source evidence

Patent IDEP4605088A1
Compound location

217;217

217;217 enlarged structure217;217 location on patent page 54
Activity table
Page 194 · table start
Page 195 · table middle
Page 196 · table end