Activity record

PGDB_A045362

Assay: % DegradationTarget: SIRT6QC: ambiguous
Activity overview

degradation = 93.6 %

TargetSIRT6
Cell lineSK-HEP-1
Concentration2 uM
Time36 h
Assay / Readout% Degradation
Assay IDPGDB_AS000778
PatentCN119019370A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001489
Compound IDPGDB_C001489
Compound6c;6c
Source record IDPGDB_C001489
InChIKeyWTLYQCBWKLMNRN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000778
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration2 uM
Treatment time36 h
Detection targetprotein_degradation
TargetSIRT6
E3Not specified
Cell lineSK-HEP-1

Source evidence

Patent IDCN119019370A
Compound location

6c;6c

6c;6c enlarged structure6c;6c location on patent page 3
Activity table
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