Assay

PGDB_AS000778

System: cell_basedTarget: SIRT6Cell line: SK-HEP-1
Assay context summary

Assay context

39 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetSIRT6
E3Not specified
Cell lineSK-HEP-1
Detection targetprotein_degradation
Activity compounds and values

Activity records

39 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001492
% Degradation-=98.9%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A013407PGDB_C001492PGDB_AS000778View
2D structure for PGDB_C001485
% Degradation-=11%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A013456PGDB_C001485PGDB_AS000778View
2D structure for PGDB_C001507
% Degradation-=56.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A013918PGDB_C001507PGDB_AS000778View
2D structure for PGDB_C001502
% Degradation-=51.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A014006PGDB_C001502PGDB_AS000778View
2D structure for PGDB_C001513
% Degradation-=72.1%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A021252PGDB_C001513PGDB_AS000778View
2D structure for PGDB_C001516
% Degradation-=89.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A022454PGDB_C001516PGDB_AS000778View
2D structure for PGDB_C001490
% Degradation-=87.1%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A022609PGDB_C001490PGDB_AS000778View
2D structure for PGDB_C001496
% Degradation-=90.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A026142PGDB_C001496PGDB_AS000778View
2D structure for PGDB_C001487
% Degradation-=20.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A030046PGDB_C001487PGDB_AS000778View
2D structure for PGDB_C001491
% Degradation-=79.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A030216PGDB_C001491PGDB_AS000778View
2D structure for PGDB_C001486
% Degradation-=98.2%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A030456PGDB_C001486PGDB_AS000778View
2D structure for PGDB_C001522
% Degradation-=97.9%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A035614PGDB_C001522PGDB_AS000778View
2D structure for PGDB_C001514
% Degradation-=87.4%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A037158PGDB_C001514PGDB_AS000778View
2D structure for PGDB_C001505
% Degradation-=15.4%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A040979PGDB_C001505PGDB_AS000778View
2D structure for PGDB_C001493
% Degradation-=17.8%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A043286PGDB_C001493PGDB_AS000778View
2D structure for PGDB_C001489
% Degradation-=93.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A045362PGDB_C001489PGDB_AS000778View
2D structure for PGDB_C001511
% Degradation-=72.4%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A047703PGDB_C001511PGDB_AS000778View
2D structure for PGDB_C001521
% Degradation-=74.8%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A050522PGDB_C001521PGDB_AS000778View
2D structure for PGDB_C001497
% Degradation-=84.8%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A053629PGDB_C001497PGDB_AS000778View
2D structure for PGDB_C001503
% Degradation-=73.6%2 uM36 hSIRT6-SK-HEP-1CN119019370APGDB_A054312PGDB_C001503PGDB_AS000778View
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