Activity record

PGDB_A045910

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

Dmax = 25 %

TargetIKZF3
Cell lineJurkat
Time24 h
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS000726
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007373
Compound IDPGDB_C007373
CompoundComparative Compound B
Source record IDPGDB_C007373
InChIKeyVACYFJWFXFNBTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000726
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Treatment time24 h
TargetIKZF3
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 101
Activity table
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Page 104 · table end