Activity record

PGDB_A046048

Assay: viabilityTarget: BTKQC: standardized
Activity overview

IC50 = 50-100 nM

TargetBTK
Cell lineNCI-H1975
Time72 h
Assay / ReadoutCCK-8 / viability
Assay IDPGDB_AS000844
PatentCN116239566A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C025809
Compound IDPGDB_C025809
CompoundGT-03287
Source record IDPGDB_C015979
InChIKeyWSIHFXFOAAVBFE-KSSJMHQNSA-N

Assay context

Assay IDPGDB_AS000844
Assay familyviability
Assay systemcell_based
Readoutviability
TechnologyCCK-8
Treatment time72 h
Detection target% Cell viability
TargetBTK
E3Not specified
Cell lineNCI-H1975
OrganismHomo sapiens

Source evidence

Patent IDCN116239566A
Compound location

GT-03287

GT-03287 enlarged structureGT-03287 location on patent page 278
Activity table
Page 844 · table start
Page 845 · table end