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SIMM · NJU
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SIMM · NJU
Activity record
PGDB_A046549
Assay: % Degradation
Target: GSPT1
QC: standardized
Activity overview
DC50 = 3.93 nM
Target
GSPT1
Cell line
HEK293
Time
24 h
Assay / Readout
DC50 / % Degradation
Assay ID
PGDB_AS000196
Patent
WO2025252247A1
QC status
standardized
Evidence details
Compound, assay context, and source
Compound
Compound ID
PGDB_C005466
Compound
化合物 13;化合物 13;化合物 13;化合物13;实施例 13;实施例 13
Source record ID
PGDB_C005466
InChIKey
DEYAENZKCOJZCD-UHFFFAOYSA-N
Assay context
Assay ID
PGDB_AS000196
Assay family
% Degradation
Assay system
cell_based
Readout
DC50
Treatment time
24 h
Detection target
protein_degradation
Target
GSPT1
E3
Not specified
Cell line
HEK293
Source evidence
Patent ID
WO2025252247A1
Compound location
化合物 13;化合物 13;化合物 13;化合物13;实施例 13;实施例 13
Activity table