Assay
PGDB_AS000196
System: cell_basedTarget: GSPT1Cell line: HEK293
Assay context summary
Assay context
Activity compounds and values
Activity records
| Structure | Metric | Control | Relation | Value | Unit | Concentration | Time | Target | E3 | Cell line | Patent | Record ID | Compound | Assay | Details |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | DC50 | - | = | 6.12 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A009168 | PGDB_C005474 | PGDB_AS000196 | View |
 | DC50 | - | = | 2.5 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A025347 | PGDB_C005473 | PGDB_AS000196 | View |
 | DC50 | - | = | 4.9 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A031373 | PGDB_C005468 | PGDB_AS000196 | View |
 | DC50 | - | = | 1.32 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A036807 | PGDB_C005472 | PGDB_AS000196 | View |
 | DC50 | - | = | 1.4 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A036940 | PGDB_C005467 | PGDB_AS000196 | View |
 | DC50 | - | = | 3.93 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A046549 | PGDB_C005466 | PGDB_AS000196 | View |
 | DC50 | - | = | 34.58 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A051267 | PGDB_C003382 | PGDB_AS000196 | View |
 | DC50 | - | = | 11.39 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A064537 | PGDB_C005475 | PGDB_AS000196 | View |
 | DC50 | - | = | 8.31 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A067345 | PGDB_C005470 | PGDB_AS000196 | View |
 | DC50 | - | = | 0.99 | nM | - | — | GSPT1 | - | HEK293 | WO2025252247A1 | PGDB_A071794 | PGDB_C005471 | PGDB_AS000196 | View |