Activity record

PGDB_A046764

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 > 10000 nM

TargetIKZF3
Time20 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS001891
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010130
Compound IDPGDB_C010130
CompoundEXAMPLE 1
Source record IDPGDB_C010130
InChIKeyFJGBXYZGWNTVFW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001891
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time20 h
Detection targetprotein_degradation
TargetIKZF3
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 75
Activity table
Page 90 · table single