Activity record

PGDB_A046880

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

EC50 = 0.5-5 nM

TargetGSPT1
Time24 h
Assay / Readoutfluorescence / EC50
Assay IDPGDB_AS002258
PatentWO2025162410A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020471
Compound IDPGDB_C020471
Compound3-4-2
Source record IDPGDB_C020471
InChIKeyRURZUZJOQPBFIS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002258
Assay family% Degradation
Assay systemcell_based
ReadoutEC50
Technologyfluorescence
Treatment time24 h
TargetGSPT1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025162410A1
Compound location

3-4-2

3-4-2 enlarged structure3-4-2 location on patent page 88
Activity table
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