Activity record

PGDB_A047187

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 >= 1000 nM

TargetGSPT1
Cell lineKG-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS002114
PatentWO2024222918A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003252
Compound IDPGDB_C003252
Compound化合物A-25
Source record IDPGDB_C003252
InChIKeyXXQVJDZPASFGKU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002114
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineKG-1

Source evidence

Patent IDWO2024222918A1
Compound location

化合物A-25

化合物A-25 enlarged structure化合物A-25 location on patent page 37
Activity table
Page 52 · table start