Activity record

PGDB_A047238

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 > 5 nM

TargetGSPT1
Cell lineHEK293T
Time7 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002143
PatentWO2025162410A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020487
Compound IDPGDB_C020487
Compound2-5-3
Source record IDPGDB_C020487
InChIKeyKENDFPFDGFPZER-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002143
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time7 d
TargetGSPT1
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDWO2025162410A1
Compound location

2-5-3

2-5-3 enlarged structure2-5-3 location on patent page 84
Activity table
Page 110 · table start